So last week Maryann had me research Resins, and after searching through the web, I have a good sense of what resins are but not really how they are going to work in labs.
Here is part of my notes:
Resin is a natural or synthetic compound which begins in a highly viscous state and hardens with treatment. Typically, resin is soluble in alcohol, but not in water. There are a number of different classes of resin, depending on exact chemical composition and potential uses. There are numerous applications for resins, ranging from art to polymer production, and many consumers interact with products which contain resin on a daily basis.
Today Maryanne took out XAD4, which is a kind of resins and set up a titration system. She explained that she had no idea if this was going to work! Basically she put some the resins at the bottom of a pipet and let the mix (Lipitor and water) run down the system. She wanted the resins to capture all the Lipitor (or atorvastatin calcium) inside. (Her thinking is that once we have water from the outside world, we can put it into this titration system to have the resins capture all the atorvastatin calcium for us to analyze.) So after the titration is over, we analyze the mix again after titration, and, sadly, the Lipitor is still in the mix. MaryAnne had me do a graph to see calculate how much did the Resins actually absorb. I just finished the graph and sent it to her. and.. unfortunately, the resins hardly absorb any. I think we will have to come up with something else! But this is still a step froward from what I have been doing :)
Peggie! I am so glad that I can understand some of your UV equipment! I am super impressed that you are able to keep all that straight because it seems so technical. I also think it is interesting that you use programs with which I am familiar, too, like the above graph. It is nice to know that our present education is flowing right into our current internships. Good luck with your research!
ReplyDeleteLove the progress that you are making, and the evolving nature of your work.
ReplyDeleteYour graph is an excellent addition to your blog.
Keep up the terrific activity!!!
Hi Peggie! I like that you posted the graph to show how much the Resins absorbed! It helped me understand what you are up to in your internship right now. I hope that you come up with another way for the Resins to absorb more! I've really liked reading all your posts so far and I'm glad that your latest trip proved as a step forward in your work!
ReplyDeleteWell done, Rose.
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